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    HomeTop StoriesGilead Sciences raises stake in cancer-centric Arcus Biosciences to 33%

    Gilead Sciences raises stake in cancer-centric Arcus Biosciences to 33%


    A sign is posted in front of the Gilead Sciences headquarters on April 29, 2020 in Foster City, California.

    Justin Sullivan | Getty Images

    Gilead Sciences said on Monday it has raised its stake in Arcus Biosciences to 33% and expanded its presence in the drug developer’s board to three, deepening their collaboration in developing cancer drugs.

    It made an equity investment of $320 million, buying Arcus stock at $21 per share, a 37.3% premium to its last closing price. Shares of Arcus rose 11.8% to $17.2 after the bell.

    Gilead said its Chief Commercial Officer Johanna Mercier will join Arcus’ board. The company had previously held a 20% stake in Arcus, according to a brokerage note by Jefferies.

    The two companies said they would discontinue a late-stage trial testing their candidate domvanalimab in combination with another experimental drug zimberelimab to treat a type of non-small cell lung cancer.

    Domvanalimab belongs to a class of treatments known as anti-TIGIT that targets a protein receptor on immune cells that acts as a brake on the immune response.

    The move comes as the companies reprioritize the joint domvanalimab development program to focus on advancing two late-stage trials testing the drug in treating lung cancer and gastrointestinal cancer.

    The trials are expected to be fully enrolled by the end of the year.

    A planned late-stage study in pancreatic cancer evaluating investigational drug quemliclustat will also become an Arcus independent study, the companies said.



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